When presidential candidate John Alexander's motorcade is ambushed by a group of terrorists, the nation is thrown into turmoil. Two weeks following the attack, Alexander is carried to victory by a sympathy vote, but his assailants have not been found, On the surface it appears to be the work of al-Qaeda, and soon the FBI and the rest of the government begin scouring the world for jihadists. But then CIA director Irene Kennedy and Special Agent Skip McMahon are presented with classified information so toxic that they consider destroying it altogether, as it contains intelligence pointing to some of the most powerful players in Washington.

Enter Mitch Rapp, the one man reckless enough to follow the evidence to its explosive conclusion. His journey takes him through the shadowy world of contract killers, into the darkest corners of the globe, and eventually back to Washington, where the fragile pillars of power are shaken to the core.